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FDA has a list of 111 HPHCs found in tobacco products and tobacco smoke and/or aerosol that are linked to cancer, cardiovascular disease, respiratory conditions, reproductive problems, and addiction

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In addition, we also derived (5) other category that encompasses conditions not included within the four main categories (psychotic disorders, bipolar disorder, sleep problems, personality disorder, eating disorders, other mental health conditions, and mental health conditions not defined), and finally, we also define two aggregated categories of (6) all mental health conditions representing records from any of the five sub-groups